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Fibrinogen beta chain Antibody

General information

Catalog number
bs-10124R
Name
Fibrinogen beta chain Antibody
Price
263.00 EUR
Size
0.1ml

Detailed information

Long name
Fibrinogen beta chain Antibody
Also known as
Fibrinogen beta chain Antibody
Category
Primary Antibodies
Conjugation
Unconjugated
Target Antigen
Fibrinogen beta chain
Specificity
This is a highly specific antibody against Fibrinogen beta chain.
Modification(s)
None
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
420-470/491
Subcellular location
Secreted
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen beta chain
Gene ID number
2244
Swiss Prot
P02675
Tested Applications
WB, IHC-P, IF(IHC-P)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity
Human, Mouse, Rat
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names
HEL-S-78p; Fibrinogen beta chain; FGB
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps