Fibrino Gens

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Fibrinogen alpha chain Antibody (FGA)

General information

Catalog number
R32595
Name
Fibrinogen alpha chain Antibody (FGA)
Price
406.00 EUR
Size
0.1mg

Detailed information

Category
Antibody
Concentration
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Form
Antigen affinity purified
Conjugation
Unconjugated
Clone
Polyclonal antibody
Recognised antigen
Fibrinogen alpha chain (FGA)
Host animal
Rabbit (Oryctolagus cuniculus)
Clonality
Polyclonal (rabbit origin)
Species reactivity
Human (Homo sapiens), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applications
WB
Recommended dilutions
Western blot: 0.5-1ug/ml
Notes
Optimal dilution of the Fibrinogen alpha chain antibody should be determined by the researcher.
Added buffer
Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2.5% BSA and 0.025% sodium azide
Intented use
This Fibrinogen alpha chain antibodyis to be used only for research purposes and not for diagnostics..
Uniprot #
P02671
Purity
Antigen affinity
Description
Fibrinogen alpha chain is a protein that in humans is encoded by the FGA gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
Immunogen
Amino acids 687-727 (RTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVE-human) were used as the immunogen for the Fibrinogen alpha chain antibody. This sequence is specific to the alpha-E isoform and not found in the alpha isoform.
Storage
After reconstitution, the Fibrinogen alpha chain antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
Localization
Secreted
Additional description
The Anti- Fibrinogen alpha chain (FGA) is a α- or alpha protein sometimes glycoprotein present in blood.
Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps