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Fibrinogen alpha chain Antibody, Cy5.5 Conjugated

General information

Catalog number
bs-7548R-Cy5.5
Name
Fibrinogen alpha chain Antibody, Cy5.5 Conjugated
Price
350.00 EUR
Size
0.1ml

Detailed information

Long name
Fibrinogen alpha chain Antibody, Cy5.5 Conjugated
Category
Conjugated Primary Antibodies
Conjugation
Cy5.5
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
Fibrinogen alpha chain
Specificity
This is a highly specific antibody against Fibrinogen alpha chain.
Modification
Unmodified
Modification site
None
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen_range
70-105/866
Subcellular location
Secreted
Source
KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain
Gene ID number
2243
Swiss Prot
P02671
Tested applications
IF(IHC-P)
Recommended dilutions
IF(IHC-P)(1:50-200)
Crossreactivity
Human, Mouse, Rat
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission
675nm/694nm
Synonyms
Fib2; Fibrinogen alpha chain; FGA
Description
The Anti-Fibrinogen alpha chain is a α- or alpha protein sometimes glycoprotein present in blood.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
Additional conjugation
Cy5.5,Cy5.5
Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
French translation
anticorps