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Fibrinogen alpha chain Antibody, ALEXA FLUOR 647

General information

Catalog number
bs-7548R-A647
Name
Fibrinogen alpha chain Antibody, ALEXA FLUOR 647
Price
380.00 EUR
Size
100ul

Detailed information

Long name
Fibrinogen alpha chain Antibody, ALEXA FLUOR 647 Conjugated
Also known as
Anti-Fibrinogen alpha chain PAb ALEXA FLUOR 647
Category
Conjugated Primary Antibodies
Conjugated with
ALEXA FLUOR® 647
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
Fibrinogen alpha chain
Specificity
This is a highly specific antibody against Fibrinogen alpha chain.
Modification
Unmodified
Modification Site
None
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
70-105/866
Subcellular location
Secreted
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain
Gene ID Number
2243
Swiss Prot
P02671
Tested applications
IF(IHC-P)
Recommended dilutions
IF(IHC-P)(1:50-200)
Crossreactivity
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Purification
Purified by Protein A.
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission
650nm/665nm
Synonyms
Fib2; Fibrinogen alpha chain; FGA
Properties
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Fibrinogen alpha chain exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation
Alexa Fluor,ALEXA FLUOR 647
Description
The Anti-Fibrinogen alpha chain is a α- or alpha protein sometimes glycoprotein present in blood.
French translation
anticorps