Fibrino Gens

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OVA Conjugated Fibrinopeptide A (FPA)

General information

Catalog number
CPB237Ra21
Name
OVA Conjugated Fibrinopeptide A (FPA)
Price
710.00 EUR
Size
100ug

Detailed information

Source
Protein conjugation
Predicted Molecular Mass(KD)
NA
Accurate Molecular Mass(KD)
NA
Organism species
Rattus norvegicus (Rat)
Item Name
Fibrinopeptide A
Alternative Names
FP-A
Research Area
Signal transduction;Hematology;
Buffer Formulation
PBS, pH7.4.
Traits
Freeze-dried powder
Purity
> 90%
Protein length
Ala20-Arg36
Tag
N-terminal His Tag
Expression System
Protein conjugation
Application
Immunogen; SDS-PAGE; WB.
Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.