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Fibrinogen gamma chain Antibody

General information

Catalog number
bs-6895R
Name
Fibrinogen gamma chain Antibody
Price
263.00 EUR
Size
0.1ml

Detailed information

Long name
Fibrinogen gamma chain Antibody
Also known as
Fibrinogen gamma chain Antibody
Category
Primary Antibodies
Conjugation
Unconjugated
Target Antigen
Fibrinogen gamma chain
Specificity
This is a highly specific antibody against Fibrinogen gamma chain.
Modification(s)
None
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
171-190/453
Subcellular location
Secreted, Helical
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen gamma chain
Gene ID number
2266
Swiss Prot
P02679
Tested Applications
WB, IHC-P, IF(IHC-P)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity
Human, Mouse, Rat
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names
Fibrinogen gamma chain; FGG; PRO2061
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps