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Fibrinogen alpha chain Antibody

General information

Catalog number
bs-7548R
Name
Fibrinogen alpha chain Antibody
Price
263.00 EUR
Size
0.1ml

Detailed information

Long name
Fibrinogen alpha chain Antibody
Also known as
Fibrinogen alpha chain Antibody
Category
Primary Antibodies
Conjugation
Unconjugated
Target Antigen
Fibrinogen alpha chain
Specificity
This is a highly specific antibody against Fibrinogen alpha chain.
Modification(s)
None
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
70-105/866
Subcellular location
Secreted
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen alpha chain
Gene ID number
2243
Swiss Prot
P02671
Tested Applications
WB, IHC-P, IF(IHC-P)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity
Human, Mouse, Rat
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names
Fib2; Fibrinogen alpha chain; FGA
Description
The Anti-Fibrinogen alpha chain is a α- or alpha protein sometimes glycoprotein present in blood.
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps